Selectivity of oxidative stress targeting in estrogen-induced experimental nephrocarcinogenesis.

Changes in expression of serine proteases HtrA1 and HtrA2 during estrogen-induced oxidative stress and nephrocarcinogenesis in male Syrian hamster.

Serine proteases HtrA1 and HtrA2 are involved in cellular stress response and development of several diseases, including cancer. Our aim was to examine the involvement of the HtrA proteins in acute oxidative stress response induced in hamster kidney by estrogen treatment, and in nephrocarcinogenesis caused by prolonged estrogenization of male Syrian hamster. We used semi-quantitative RT-PCR to ...

P-207: Deltamethrin-Induced Derangements Correlates with Estrogen Synthesis, Angiogenesis and Oxidative Stress

Background: Deltamethrin (DTM) is a pyrethroid derivative, which is the most potent products of Type 2 insecticides and acts by delaying the closure of sodium channels. Estrogen as a vascular growth factor on ovarian tissue plays an essential impact further to its involvement in follicular growth. On the other hand, the role of angiogenesis on ovarian tissue in inhibiting the apoptotic provoker...

P-216: Dual Targeting of TNF-? and Free Radicals Toxic Stress as A Promising Strategy to Manage Experimental Polycystic Ovary

P-58: BSO-Induced Oxidative Stress Affects Testicular Ultrastructure, Levels of Oxidative Markers, Testosterone and Sperm Fertility

Background: GSH is the main intracellular antioxidant and its level is important for protecting cell from oxidative stress. BSO inhibits GSH synthesis and cause oxidative stress. The study is designed to investigate the effect of BSO induced oxidative stress on testicular histology, semen parameters and sperm fertility. Materials and Methods: The adult male mice were divided into two groups of ...

The effects of Intracerebellumal Injection of Estrogen on Anxiety-like Behavior and Parameters of Antioxidant System following Ethidium Bromide Injection in rat

Background & Objectives: Demyelination by Ethidium bromide is one of the ways that is usually used for preparing experimental models of MS. Treatment with estrogen protects oligodendrocyts from cell poisoning and stops lipidic peroxidation. The aim of this study is the evaluation of the effects of estrogen on anxiety like behavior and stress oxidative parameters after inducing demyelination by ...